The Optilume® drug-coated balloon was developed in response to severe patient and physician dissatisfaction with current stricture solutions.
This proprietary technology combines balloon dilation and drug delivery and is well-tolerated by patients. Rapid uptake of the highly lipophilic drug, paclitaxel, limits hyperactive cell proliferation and the fibrotic scar tissue generation that results in stricture recurrence.
For additional clinical information regarding Optilume® for the treatment of urethral stricture, please click below.
CAUTION – Investigational device in the United States. Limited by federal law to investigational use.
A urethral stricture is a narrowing caused by scarring of the lining of the urethra and the surrounding corpus spongiosum. Strictures can range from less than 1cm long to those that extend the entire length of the urethra. They can occur at any point along the urethra but are most often seen in the bulbar region.
With minor strictures, there may be less signs of any symptoms. With tighter strictures, patients may experience one or more of the following:
A stricture can act as a “bottleneck” which prevents complete bladder emptying. This can cause the patient to retain urine in their bladder after they pass urine, which can result in bladder, prostate or kidney infections, and lead to the formation of stones. All of these conditions can cause long-term bladder damage and kidney failure.
Many types of treatment are available, ranging from conservative or minimally invasive procedures, right through to complex reconstructive operations. The goal of treatment is to relieve the symptoms caused by the stricture and, if possible, to reduce the risk of the stricture returning.
The type of treatment recommended by Urology healthcare professionals depends on several factors:
For more information on the types of treatment available for the treatment of urethral stricture please visit the British Association of Urological Surgeons website and view their ‘general information about urethral stricture disease leaflet’ https://www.baus.org.uk/_userfiles/pages/files/Patients/Leaflets/Urethral%20stricture%20disease.pdf