What is Impedance?
Impedance measurement can be used to assist in detecting GERD (Gastroesophageal Reflux Disease) and distinguish acid and weakly acidic refluxes causing symptoms.
Gastroesophageal Reflux Disease (GERD) is caused by the reflux of gastric contents into the esophagus. Typical patient symptoms are heartburn, regurgitation, and chest pain. These patient groups are often on PPI medication, but non-acidic reflux can still cause symptoms.
Traditional pH recording only records acidic pH reflux episodes. Impedance-pH detects both acidic and non-acidic reflux episodes.
Combined Impedance-pH recording is clinically useful in the evaluation of symptoms under PPI therapy, as well as for hoarseness, unexplained cough, and applications of particular interest  .
Laborie is passionate about bringing freedom and dignity to patients suffering from gastroenterological diseases and disorders through innovation in diagnostic and treatment options. We work with leading clinician-researchers and local universities to incorporate the most recent advancements and technical knowledge into our products while reflecting practical realities of the typical GI clinic.
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2] Savarino E, Marabotto E, Zentilin P, Frazzoni M, Sammito G, Bonfanti D, Sconfienza L, Assandri L, Gemignani L, Malesci A, Savarino V. The added value of impedance-pH monitoring to Rome III criteria in distinguishing functional heartburn from non-erosive reflux disease. Dig Liver Dis. 2011 Jul;43(7):542-7.